Volume 2, Issue 1 And 2 (3-2019)                   زیست شناسی 2019, 2(1 And 2): 92-99 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bagoghli N, Moghimi H. Harnessing the power of evolution for biotechnology by adaptive laboratory evolution (ALE) approach. زیست شناسی. 2019; 2 (1 and 2) :92-99
URL: http://ijbio.ir/article-1-259-en.html
Dept. of Microbial Biotechnology, School of Biology, College of Science, University of Tehran, Tehran, I.R. of Iran , hmoghimi@ut.ac.ir
Abstract:   (737 Views)
Adaptive laboratory evolution (ALE) due to its simplicity and effectiveness have been used to improve important industrial straits properties such as carbon source utilization, stability in unpleasant environmental conditions and tolerance to chemical inhibitors. No need for prior genetic knowledge of desired strain makes ALE as a powerful approach for strain development even for species with minimal genotypic information. While the procedures for adaptive laboratory evolution has remained similar for many years, recent advances promise for improving the experimental workflows for evolutionary engineering by accelerating the pace of evolution and simplifying the analysis of evolved strains. The aim of this review is highlighting recent advances in this area and evaluation of this technique application in biotechnology.
     
Type of Study: Community |
Received: 2019/07/24 | Accepted: 2019/07/24 | Published: 2019/07/24

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2019 All Rights Reserved | Biological Science Promotion

Designed & Developed by : Yektaweb